Publications

  1. D. Yu and C. Bae, “Propofol inhibits Piezo mechanosensitive channels,” Biophys J. 2025 Jun 7:S0006-3495(25)00348-0. doi: 10.1016/j.bpj.2025.06.005. Epub ahead of print. Erratum in: Biophys J. 2025 Aug 8:S0006-3495(25)00497-7. doi: 10.1016/j.bpj.2025.08.004. PMID: 40485107.
  2. Ikiz, E. Hascup, C. Bae, and K. Hascup, “Microglial Piezo1 mechanosensitive channel as a therapeutic target in Alzheimer’s disease,” Frontiers in Cellular Neuroscience. 2024 June 18;18:1423410. doi: 10.3389/fncel.2024.1423410. PMID: 38957539; PMCID: PMC11217546.
  3. D. Yu, A. Ahmed, J. Jayasi, A. Womac, O. Sally, and C. Bae, “Inflammation condition sensitizes Piezo1 mechanosensitive channel in mouse cerebellum astrocyte,” Frontiers in Cellular Neuroscience. 2023 May 25;17:1200946. doi: 10.3389/fncel.2023.1200946. PMID: 37305437; PMCID: PMC10248153.
  4. X. Liu, C. Bae, B Liu, Y. Zhang, X. Zhou, D. Zhang, C. Zhou, A. DiBua, L. Schutz, M. Kaczocha, M. Puopolo, T. Yamaguchi, JM Chung, and S. Tang, “Development of opioid-induced hyperalgesia depends on reactive astrocytes controlled by Wnt5a signaling,” Molecular Psychiatry. 2023 Feb;28(2):767-779. doi: 10.1038/s41380-022-01815-0. Epub 2022 Oct 6. PMID: 36203006; PMCID: PMC10388343.
  5. X. Liu, C. Bae, B. Gelman, JM Chung, and S. Tang, “A neuron-to-astrocyte Wnt5a signal governs astrogliosis during HIV-associated pain pathogenesis,” Brain. 2022 Nov 21;145(11):4108-4123. doi: 10.1093/brain/awac015. PMID: 35040478; PMCID: PMC10200293.
  6. A. Kearns, J. Jayasi, X. Liu, J. Wang, Y. Shi, JM Chung, JH la, S. Tang, and C. Bae, “Neuron type-dependent synaptic activity in the spinal dorsal horn of opioid-induced hyperalgesia mouse model,” Frontiers in Synaptic Neuroscience. 2021 Nov 18;13:748929. doi: 10.3389/fnsyn.2021.748929. PMID: 34867259; PMCID: PMC8637419.
  7. KY Lee, C. Bae, D Lee, Z Kagan, K Bradley, JM Chung, JH La, “Low-intensity, kilohertz frequency spinal cord stimulation differently affects excitatory and inhibitory neurons in the rodent superficial dorsal horn,” Neuroscience. 2020 Jan 21;428:132-139. doi: 10.1016/j.neuroscience.2019.12.031. Epub 2020 Jan 7. PMID: 31917342.
  8. W. Ru, Liu X, C. Bae, Y. Shi, R. Walikonis, J. Chung, and S. Tang, “Microglia mediate HIV-1 gp120-induced synaptic degeneration in spinal pain neural circuits,” Journal of Neuroscience. 2019 Oct 16;39(42):8408-8421. doi: 10.1523/JNEUROSCI.2851-18. 2019. Epub 2019 Aug 30. PMID: 31471472; PMCID: PMC6794928.
  9. HS Sim, C. Bae, J. Wagn, KH Lee, K. Hankerd, H. Kim, J. Chung, and J. La, “Peripheral and central oxidative stress in chemotherapy-induced neuropathic pain,” Molecular Pain. 2019 Jan-Dec;15:1744806919840098. doi: 10.1177/1744806919840098. PMID: 30857460; PMCID: PMC6458664.
  10. R. Gnanasambandam, C. Bae, L. Ziegler, F. Sachs, P. Gottlieb, “Functional analyses of heteromeric human PIEZO1 Channels,” PLoS One. 2018 Nov 21;13(11):e0207309. doi: 10.1371/journal.pone.0207309. PMID: 30462693; PMCID: PMC6248943.
  11. C. Bae, J. Wang, H. Shim, S. Tang, J. Chung, and J. La, “Mitochondrial superoxide increases excitatory synaptic strength in spinal dorsal horn neurons of neuropathic mice,” Molecular Pain. 2018 Jan-Dec;14:1744806918797032. doi: 10.1177/1744806918797032. PMID: 30152257; PMCID: PMC6113735.
  12. J. La, J. Wang, A. Bittar, H. Shim, C. Bae, and J. Chung, “Differential involvement of reactive oxygen species in capsaicin-induced secondary mechanical hyperalgesia and tactile allodynia,” Molecular Pain. 2017 Jan-Dec;13:1744806917713907. doi: 10.1177/1744806917713907. PMID: 28587509; PMCID: PMC5466348.
  13. C. Cox, C. Bae, L. Ziegler, S. Hartley, V. Nikolova-Krstevski, P. Rohde, F. Sachs, P. Gottlieb, and B. Martinac, “Removal of the mechanoprotective influence of the cytoskeleton reveals PIEZO1 is gated by bilayer tension,” Nature Communications. 2016 Jan 20;7:10366. doi: 10.1038/ncomms10366. PMID: 26785635; PMCID: PMC4735864.
  14. C. Bae, T. Suchyna, L. Ziegler, F. Sachs, and P. Gottlieb, “Human PIEZO1 ion channel functions as a split protein,” PLoS One. 2016 Mar 10;11(3):e0151289. doi: 10.1371/journal.pone.0151289. PMID: 26963637; PMCID: PMC4786117.
  15. C. Bae, F. Sachs, and P. Gottlieb, “Protonation of human PIEZO1 ion channel stabilizes inactivation,” Journal of Biological Chemistry. 2015 Feb 20;290(8):5167-5173. doi: 10.1074/jbc.M114.604033. Epub 2015 Jan 5. PMID: 25561736; PMCID: PMC4335250.
  16. R. Gnanasambandam, C. Bae, P. Gottlieb, and F. Sachs, “Ionic selectivity and permeation properties of human PIEZO1 channel,” PLoS One. 2015 May 8;10(5):e0125503. doi: 10.1371/journal.pone.0125503. PMID: 25955826; PMCID: PMC4425559.
  17. C. Bae, R. Gnanasambandam, C. Nicolai, F. Sachs, and P. Gottlieb, “Xerocytosis is caused by mutations that alter the kinetics of the mechanosensitive channel Piezo1,” Proceedings of the National Academy of Sciences, USA (PNAS). 2013 Mar 19;110(12):E1162-8. doi: 10.1073/pnas.1219777110. Epub 2013 Mar 4. PMID: 23487776; PMCID: PMC3606986.
  18. C. Bae, F. Sachs, and P. Gottlieb, “Human PIEZO1: Removing inactivation,” Biophysical Journal. 2013 Aug 20;105(4):880-6. doi: 10.1016/j.bpj.2013.07.019. PMID: 23972840; PMCID: PMC3752115.
  19. H. Huang, C. Bae, F. Sachs, and T. Suchyna, “Caveolae regulation of mechanosensitive channel function in myotubes,” PLoS One. 2013 Aug 30;8(8):e72894. doi: 10.1371/journal.pone.0072894. PMID: 24023653; PMCID: PMC3758351.
  20. P. Gottlieb, C. Bae, and F. Sachs, “Gating the mechanical channel Piezo1: A comparison between whole-cell and the patch recording,” Channels (Austin). 2012 Jul-Aug;6(4):282-9. doi: 10.4161/chan.21064. Epub 2012 Jul 1. PMID: 22790451; PMCID: PMC3508907.
  21. C. Bae, I. Park, and P. Butler, “Assessing the nano-dynamics of the cell surface,” Journal of the Korean Society for Nondestructive Testing, 2012, 32(3): 263-268.
  22. C. Bae, V. Markin, T. Suchyna, and F. Sachs, “Modeling ion channels in the gigaseal,” Biophysical Journal. 2011 Dec 7;101(11):2645-51. doi: 10.1016/j.bpj.2011.11.002. PMID: 22261052; PMCID: PMC3297810.
  23. C. Bae, F. Sachs, and P. Gottlieb, “The mechanosensitive ion channel Piezo1 is inhibited by the peptide GsMTx4,” Biochemistry. 2011 Jul 26;50(29):6295-300. doi: 10.1021/bi200770q. Epub 2011 Jun 29. PMID: 21696149; PMCID: PMC3169095.
  24. D. Fuentes, C. Bae, and P. Butler, “Focal adhesion induction at the tip of a functionalized nanoelectrode,” Cellular and Molecular Bioengineering. 2011 Dec;4(4):616-626. doi: 10.1007/s12195-011-0214-7. PMID: 22247742; PMCID: PMC3256556.
  25. C. Bae and P. Butler, “Finite element analysis of microelectrotension of cell membranes,” Biomechanics and Modeling in Mechanobiology. 2008 Oct;7(5):379-86. doi: 10.1007/s10237-007-0093-y. Epub 2007 Jul 27. PMID: 17657517; PMCID: PMC3251963.
  26. C. Bae and P. Butler, “Automated single-cell electroporation,” Biotechniques. 2006 Oct;41(4):399-400, 402. doi: 10.2144/000112261. PMID: 17068953; PMCID: PMC3251211.
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